Functional Target Validation (FTV)


Fluofarma, one of NDI’s partner companies, has developed a technology that enables identification of lead compounds based on their biological effects on identified targets, at the earliest stages of drug discovery.
 
Technology:
 
The proprietary technology, based on automated flow cytometry, combines cell-based assays with large–scale analysis. It allows a functional analysis of several molecular events simultaneously in single cells.
 
Services for drug discovery:
-       Functional target validation
-       Library screening for chemical entities, crude extracts, proteins or gene collections
-       Lead selection and optimization
-       Compound profiling and mechanism of action studies
 
Key Features:
-       Functional measuring: Assessment of molecular events in living neurons
-       Multiplexing:  Measurement of up to 5 parameters simultaneously in single cells
-       Large-scale: 2000 wells tested per day with 2500 cells analyzed individually per well

For more information on Functional Target Validation, click here.

For more information on FTV screening list, click here.