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Preclinical contract research: animal models of neurological disorders:

Preclinical Multiple Sclerosis models (MS models)

            Multiple sclerosis is most often modeled in vivo by induction of experimental autoimmune encephalopathy (EAE), in rats or mice.  NDI offers the most-often used versions of this model, induction with myelin basic protein (MBP) in rats, and with the myelin oligodendrocyte glycoprotein (MOG) in mice.

(For an example study [Click here])



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