Scopolamine-impaired adult rats, using standard water maze
(For an example contract study [Click here])
Naturally aged rats, using novel foraging/hoarding task
(For a published example of contract study [Click here])
Audiogenic seizures in Tg2576 and FRA x AD mice
(For examples of this model [Click here1, Click here2])
Dog (aged beagle)
Age-related declines in memory, activity, and social interaction correlated with cortical atrophy and plaque load, plus cerebral atrophy. Age-related sleep disruptions also shown with EEG.
(For further details [Click here])
DMTS test in dogs (above)
In vitro assays
Abeta-induced neuron loss, with assays distinguishing test compounds that are either neuroprotective vs. neurotrophic
(For a redacted final report of contract study [Click here]).
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