NeuroDetective International Home Expert Contract Research, Advancing Drug Development

Preclinical contract research: animal models of neurological disorders:

Preclinical Alzheimer's models (AD models


Scopolamine-impaired adult rats, using standard water maze

(For an example contract study [Click here])

Naturally aged rats, using novel foraging/hoarding task

(For a published example of contract study [Click here])



Audiogenic seizures in Tg2576 and FRA x AD mice

(For examples of this model [Click here1, Click here2])


Dog (aged beagle)

     Age-related declines in memory, activity, and social interaction correlated with cortical atrophy and plaque load, plus cerebral atrophy.  Age-related sleep disruptions also shown with EEG. 

(For further details [Click here])




                                   DMTS test in dogs (above)

Monkey (aged Rhesus)

For further information on this model, see our NHP studies page



In vitro assays

     Abeta-induced neuron loss, with assays distinguishing test compounds that are either neuroprotective vs. neurotrophic

(For a redacted final report of contract study [Click here]).


For more information on our AD models, click here

  [Back to animal models list]


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