|
|
 |
|
Mouse
- 1-methyl 4-phenyltetrahydropyridine (MPTP) lesion
- Skilled reaching test
- Supported vs. unsupported rearing
- Tail-hang test
- Open Field activity
Rat
- 6-hydroxydopamine (6-OHDA) lesion, unilateral and bilateral
- Skilled reaching test
- Akinesia test
- Forelimb asymmetry (cylinder) test
- Staircase test
- Amphetamine induced rotation
- Vacuous chewing (dyskinesia measure)
- Rotenone lesion (low-dose, high-dose)
Primate
- MPTP lesion
- Parkinsonism activity scale
- Delayed Non-Match to Position test
- DPPH (determination of radical scavenging potential)
- Immunocytochemical determination of TH levels in substantia nigra and striatum
- Evaluation of dopamine release in striatum
- Evaluation of neuron survival in substantia nigra
In vitro assays
|
|
 |
|
