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Preclinical contract research: animal models of neurological disorders:

Preclinical Stroke models

Large-vessel occlusion (modified MCAO)

This new model mimics a particular clinical condition seen following ischemic stroke, large vessel occlusion, and permits direct delivery of a potential therapeutic to the injury site.  Focal ischemia is first induced by occlusion of the CCA/MCA, followed by rapid recanalization, then direct IA injection of a potential neurotherapeutic agent.  Click here for a full description of this model.



     For examples of contract stroke studies from NDI laboratories                                   [Click here1, Click here2]



For more information on our Stroke models, click here.

 [Back to animal models list]




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