A contract research network of neuroscientists

Sleep EEG

Since 2002, 72% of all NDI studies have come from repeat clients.
NeuroDetective International:  Pre-clinical Contract Research Organization, Pharmaceutical disorders research and testing

Sleep EEG
 


 

Potential therapies for insomnia, apnea, and other sleep disorders are typically evaluated in animal models with electrophysiological endpoints, in particular using electroencephalogram measures (EEG).  NDI offers both rat and dog models for EEG measuring, plus behavioral measures for canines.  Specific endpoints include:

• Description of sleep architecture (latency and duration of sleep stages)
• Sleep maintenance
• Sleep/ wakefulness cycles
• Sleep physiology evaluation via EEG in freely moving animals
• Changes in activity (dog) as a measure of setting/resetting of the circadian clock
• Continuous measurement of food consumption over circadian cycles (dog)
• Motor activity during the light/dark cycle (dog).
• REM and NREM sleep patterns, including the following parameters:

- REM
- NREM
- Continuity
- Sleep bout duration

 

 

 

 

 

 

 

 

 

 

 

 

 

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